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"My immune function has significantly improved since taking this product over the past year." Jesse H.
Rated 4.8 out of 5 stars
144 Reviews

Advanced Biotic

Advanced Biotic

Levels up your cellular defenses against all types of microbe threats
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  • advanced_biotic_microbiome_balance - Vital Plan

    Promotes whole-body microbiome balance*

  • advanced_biotic_secondary_support_gut_flora - Vital Plan

    Secondary support for gut flora*

  • advanced_biotic_respiratory_liver_antioxidant - Vital Plan

    Offers respiratory, liver, and antioxidant support*

  • advanced_biotic_immune_function_support - Vital Plan

    Supports immune function and helps maintain the natural healing systems of the body*

Support Your Body’s Microbiome

Shortly after birth, you inherit microbes from your mother and the surrounding environment. The total of all the microbes that call your body home is called the microbiome. With more than 40,000 species possible and an infinite number of possible combinations, your microbiome is unique from every other person’s on the planet.

Though it was once thought that the microbes of the body were isolated mostly to the gut and skin, more recent research has revealed that ultra-low concentrations of microbes exist in all the tissues of your body — including your blood, heart, and even your brain.

Your health is very dependent on the health of your microbiome. As you go through life you continue to add microbes to your microbiome; maintaining a healthy immune system is essential for preserving the balance of “good” and “bad” microbes.

The herbs in Advanced Biotic work in two ways:

  1. They help maintain microbiome balance directly
  2. They support the immune system, which has the big job of managing the menagerie of microbes that inhabit the body.
  • andrographis-detoxifying-antioxidantanti-inflammatory_dd12dc10-b4f4-4954-9aef-9850eadeac09 - Vital Plan

    AP-Bio™ Andrographis Extract

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  • cats-claw-bark-nootropic-brain-health-circle - Vital Plan

    Cat's Claw Extract

  • immune-boosting-herb-japanese-knotweed - Vital Plan

    Japanese Knotweed Extract

  • immune-boosting-food-garlic - Vital Plan


  • sarsaparilla-detox-endotoxins-microbial-dieoff_cc177039-07f7-4c39-9536-335f6998dc23 - Vital Plan


From Dr. Bill Rawls:

"Advanced Biotic is for when you need to level up your defenses against both internal and external microbe threats. It keeps them in check so you stay healthy. "

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Inside Advanced Biotic

Each ingredient in Advanced Biotic brings an impressive spectrum of benefits to the table. Combined, they provide comprehensive coverage with clinical grade herbs at serving sizes based as closely as possible on research and traditional use to ensure maximum efficacy for immune and microbiome support. These are herbs that Dr. Rawls has personally used and trusted for decades.

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What’s Inside Matters

At Vital Plan, we pride ourselves on using clear, honest labeling. Advanced Biotic is quality-tested multiple times throughout the manufacturing process, then sent to third-party labs for verification of ingredient purity and label claims.

The serving sizes for each herb in this product match the corresponding research and traditional use as closely as possible to ensure maximum efficacy. In addition, the amounts of each herb are clearly indicated for you and your healthcare practitioner, so you know exactly what you are putting into your body.

Advanced Biotic is Gluten-Free, GMO Free, Vegan, Vegetarian, Peanut-Free, Egg-Free, Dairy-Free, and Soy-Free. This product is also free from Fish, Shellfish, Artifical Dyes, BSE/TSE, Non-ETO/Non-Irradiated

Quality at every Step

Advanced Biotic Quality Standards

✓ Researched and formulated by Bill Rawls, MD

✓ Clinical-grade, optimally-dosed herbs

✓ Backed by science and a long history of traditional use

✓ Transparent labelling with no hidden ingredients or “proprietary blends”

✓ Independently lab tested for purity and potency

Suggested Use

For ongoing immune and microbiome support, take 3 capsules of the formulation once a day, ideally with food and plenty of liquid.

For more acute immune and microbiome support, increase servings to 3 capsules of the formulation twice daily, ideally with food and plenty of liquid, for as long as needed.

Consult your healthcare provider before using this product if you have a medical condition, are pregnant or nursing, or are taking medications.

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What our Customers Say:

"I love this supplement!"

"I love this supplement! I definitely feel that my immune health is supported when I take it. I’ve also noticed other benefits to my digestive system when I take it… as soon as I stop taking it, I can tell the difference. Highly recommend! "

Lynndsi M.
Advanced Biotic Customer

What Our Customers Say

Total 5 star reviews: 129 Total 4 star reviews: 8 Total 3 star reviews: 5 Total 2 star reviews: 0 Total 1 star reviews: 2
Rated 4.8 out of 5 stars
Based on 144 reviews
98%would recommend this product
144 reviews
  • TB
    Tris B.
    Verified Buyer
    12 seconds ago
    Advanced Biotic
    Advanced Biotic
    Rated 5 out of 5 stars
    Seems to work great

    This seems to be working well for my husband so far:)

  • S
    Verified Buyer
    4 days ago
    Advanced Biotic
    Advanced Biotic
    Rated 5 out of 5 stars

    This product will take you to the next level. I would recommend this for those who want to experience noticeable benefits. Twice per day is best.

  • SS
    Sue Savod S.
    Verified Buyer
    3 weeks ago
    Advanced Biotic
    Advanced Biotic
    Rated 5 out of 5 stars
    Great Product!

    I have used this for a couple years. Really helped my **** and Bartonella - both chronic after years of anti biotic. Still test positive. So I thought I was good. Then I got long *****. Very serious. Lots of pain, fatigue and brain fog. So now I will try double for that. I have recommended you to several **** patients.

    Sue Savod, Napa

  • KF
    Karyn F.
    Verified Buyer
    1 month ago
    Advanced Biotic
    Advanced Biotic
    Rated 5 out of 5 stars
    Promotes good health

    These herbs are potent and promoting my health

  • SW
    Shannon W.
    Verified Buyer
    1 month ago
    Advanced Biotic
    Advanced Biotic
    Rated 5 out of 5 stars
    Natural **** antibiotic

    Best supplement I have used for my **** and coinfection protocol.

  • SL
    Sherry L.
    Verified Buyer
    1 month ago
    Advanced Biotic
    Advanced Biotic
    Rated 5 out of 5 stars
    Great Product

    I have used it daily for about 5 years and keeps with chronic ***** Mountain Spotted Fever at bay.

  • SM
    Stephanie M.
    Verified Buyer
    1 month ago
    Advanced Biotic
    Advanced Biotic
    Rated 5 out of 5 stars
    Amazing products

    I have been using this product and the other 3 Restore supplememts for 10 years now and can honestly attribute it to my great health!

  • SP
    Steven P.
    Verified Buyer
    2 months ago
    Advanced Biotic
    Advanced Biotic
    Rated 5 out of 5 stars
    Key component to healing

    Advanced biotic and adaptogen recovery were critical components to our family’s ability to recover from **** disease. We still incorporate these herbs through cycles for overall health maintenance.

  • C
    Flag of United States
    8 months ago
    Advanced Biotic
    Advanced Biotic
    Rated 3 out of 5 stars
    Strange reaction

    I can tolerate Advanced Biotic in small doses of one to three capsules per day, but more than that causes a feeling of stress in my brain and gives me a headache. I was told by Vital Plan staff to reduce the dosage, and that helps, but I’m not sure if this product helps since I was taking it in conjunction with all of the 3 other Restore Kit products for the treatment of chronic Lyme disease. Anyway, after 15 or 16 months on the Restore Kit, my energy has returned, so that I am able to do some work and exercise, so maybe the Restore Kit works. I still have trouble sleeping and cannot take the Vital Plan sleep product because I cannot tolerate melatonin. I know it sounds weird, but melatonin makes me cry uncontrollably. I read that can happen to people who are prone to depression which I have always been.

    Vital Plan
    7 months ago
    Hi Cynthia. Thank you so much for your review. We are happy to know you are experiencing some improvements. Although you are taking a reduced serving that you tolerate of the Advanced Biotic formula it is still helping.
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It's Okay to Have Questions!

More Information About Advanced Biotic

What is the recommended serving plan for this product?

For ongoing immune support, take 3 capsules of each formulation once a day, ideally with food and plenty of liquid.

For acute immune support when you feel like your immune system or microbiome is under increased strain, increase servings to 3 capsules of twice daily, ideally with food and plenty of liquid.

Consult your healthcare provider before using this product if you have a medical condition, are pregnant or nursing, or are taking medications.

When should I take Advanced Biotic?

For ongoing immune and microbiome support, simply take 3 capsules once a day. Ideally, take with food and a glass of water, in the morning.

For acute immune and microbiome support, increase the serving size to 6 capsules per day. You can take 3 with breakfast and 3 with dinner. Or, take 2 with breakfast, lunch, and dinner for more sustained immune and microbiome support throughout the day.

Should I take this product with food and liquids?

It’s ideal to take this product with food and water to increase activation and absorption of the ingredients. However, it’s not critical, and the majority of benefits will still be gained if taken without food or water

When does this formulation usually start to work?

The herbs in Advanced Biotic get to work immediately. To maximize cumulative benefits for ongoing support, we recommend taking this product for at least 2-4 weeks, however, it may be taken longer if needed.

For acute immune support, take double the serving for 2-3 days, or longer as needed.

Is this product gluten-free?

Our products are 100% gluten-free.

Does this product contain caffeine or other stimulants?

This product does not contain caffeine or any other stimulants.

Is this product for women and men?

Yes, this formula is designed to benefit both women and men.

Why are there 3 capsules? Can I just take 1 capsule?

Dr. Rawls and the formulation team at Vital Plan suggest taking the full 3-capsule serving in order to get optimal benefits from these herbs. The serving sizes of each ingredient are based as closely as possible on the amounts shown to be effective in clinical use, research studies, and/or traditional use.

Some other products on the market may contain the same ingredients in this formulation, but at levels much too low to provide significant benefit. In some cases, other brands may have proprietary blends that prevent you from seeing how much of a certain ingredient you are receiving.

How do I know Vital Plan products are safe?

Our extensive quality-control measures are documented on this website. Each of our products comes with an independent certificate of analysis verifying the ingredient identity, purity, and standardized constituents, where applicable. This includes testing for heavy metals, organic toxins, and microbiological contaminants.

We work closely with only select manufacturing partners who follow the highest GMP (Good Manufacturing Processes) guidelines, and each batch of products is tested thoroughly during the manufacturing process. We are passionate about quality, and we would never offer anything to the public that we would not take ourselves.

What if I am taking prescription medications or have a medical condition?

As with any new supplement, we recommend you check with your healthcare provider before using this product if you are taking medications.

Is this product safe for pregnant and breastfeeding women, or for couples trying to become pregnant?

Avoid use of this product while pregnant or breastfeeding, or if trying to become pregnant.

Are there any other contraindications?

Consult with your healthcare provider before starting any new supplement if you have any medical conditions.

  • Formulated-By-Dr.-Bill-Rawls - Vital Plan

    Formulated by Dr. Bill Rawls

  • Products-made-in-the-USA - Vital Plan

    Made in the USA

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    Money-Back Guarantee

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    Free US Shipping Over $100

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We are Physician-Led & Science-Backed

In a quest to regain his own health after a debilitating illness, Dr. Rawls poured his soul into understanding the underlying causes of poor health and how to regain and maintain good health from a holistic view-point.

His research led him deep into the world of herbs where he discovered their transformative power in promoting good health.

*These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.